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» Algorithmic strategies for the single nucleotide polymorphis...
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ISMB
2000
13 years 7 months ago
A Practical Algorithm for Optimal Inference of Haplotypes from Diploid Populations
The next phase of human genomics will involve largescale screens of populations for signi cant DNA polymorphisms, notably single nucleotide polymorphisms SNP's. Dense human S...
Dan Gusfield
BMCBI
2004
112views more  BMCBI 2004»
13 years 6 months ago
A double classification tree search algorithm for index SNP selection
Background: In population-based studies, it is generally recognized that single nucleotide polymorphism (SNP) markers are not independent. Rather, they are carried by haplotypes, ...
Peisen Zhang, Huitao Sheng, Ryuhei Uehara
BMCBI
2006
138views more  BMCBI 2006»
13 years 6 months ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...
BMCBI
2011
12 years 9 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
BMCBI
2005
67views more  BMCBI 2005»
13 years 6 months ago
Selecting additional tag SNPs for tolerating missing data in genotyping
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
Yao-Ting Huang, Kui Zhang, Ting Chen, Kun-Mao Chao