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» Algorithms and Constraint Programming
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137
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BMCBI
2010
153views more  BMCBI 2010»
15 years 21 days ago
MimoSA: a system for minimotif annotation
Background: Minimotifs are short peptide sequences within one protein, which are recognized by other proteins or molecules. While there are now several minimotif databases, they a...
Jay Vyas, Ronald J. Nowling, Thomas Meusburger, Da...
109
Voted
BMCBI
2008
110views more  BMCBI 2008»
15 years 20 days ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
127
Voted
BMCBI
2008
116views more  BMCBI 2008»
15 years 20 days ago
Clustering exact matches of pairwise sequence alignments by weighted linear regression
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
Alvaro J. González, Li Liao
121
Voted
BMCBI
2008
111views more  BMCBI 2008»
15 years 20 days ago
A perl package and an alignment tool for phylogenetic networks
Background: Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of evolutionary events acting at the population level, like recombin...
Gabriel Cardona, Francesc Rosselló, Gabriel...
93
Voted
BMCBI
2008
119views more  BMCBI 2008»
15 years 20 days ago
Integrated multi-level quality control for proteomic profiling studies using mass spectrometry
Background: Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue fo...
David A. Cairns, David N. Perkins, Anthea J. Stanl...
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