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» Algorithms and computations on cellular automata
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97
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GECCO
2008
Springer
117views Optimization» more  GECCO 2008»
15 years 1 months ago
CrossNet: a framework for crossover with network-based chromosomal representations
We propose a new class of crossover operators for genetic algorithms (CrossNet) which use a network-based (or graphbased) chromosomal representation. We designed CrossNet with the...
Forrest Stonedahl, William Rand, Uri Wilensky
127
Voted
BMCBI
2006
122views more  BMCBI 2006»
15 years 19 days ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
ISAAC
2003
Springer
133views Algorithms» more  ISAAC 2003»
15 years 5 months ago
The Intractability of Computing the Hamming Distance
Given a string x and a language L, the Hamming distance of x to L is the minimum Hamming distance of x to any string in L. The edit distance of a string to a language is analogous...
Bodo Manthey, Rüdiger Reischuk
BMCBI
2007
157views more  BMCBI 2007»
15 years 21 days ago
A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
Background: The fundamental role that intrinsic stochasticity plays in cellular functions has been shown via numerous computational and experimental studies. In the face of such e...
Asawari Samant, Babatunde A. Ogunnaike, Dionisios ...
129
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RECOMB
2010
Springer
15 years 2 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael