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ISAAC
1998
Springer
99views Algorithms» more  ISAAC 1998»
15 years 1 months ago
On the Multiple Gene Duplication Problem
Abstract. A fundamental problem in computational biology is the determination of the correct species tree for a set of taxa given a set of possibly contradictory gene trees. In rec...
Michael R. Fellows, Michael T. Hallett, Ulrike Ste...
STOC
2010
ACM
224views Algorithms» more  STOC 2010»
15 years 1 months ago
Satisfiability Allows No Nontrivial Sparsification Unless The Polynomial-Time Hierarchy Collapses
Consider the following two-player communication process to decide a language L: The first player holds the entire input x but is polynomially bounded; the second player is computa...
Holger Dell and Dieter van Melkebeek
71
Voted
ICFP
2010
ACM
14 years 10 months ago
Distance makes the types grow stronger: a calculus for differential privacy
We want assurances that sensitive information will not be disclosed when aggregate data derived from a database is published. Differential privacy offers a strong statistical guar...
Jason Reed, Benjamin C. Pierce
BMCBI
2010
89views more  BMCBI 2010»
14 years 9 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...
BMCBI
2010
160views more  BMCBI 2010»
14 years 9 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang