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» Algorithms for Finding Gene Clusters
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ICML
2009
IEEE
16 years 17 days ago
Sparse Gaussian graphical models with unknown block structure
Recent work has shown that one can learn the structure of Gaussian Graphical Models by imposing an L1 penalty on the precision matrix, and then using efficient convex optimization...
Benjamin M. Marlin, Kevin P. Murphy
RECOMB
2005
Springer
16 years 2 days ago
Predicting Transcription Factor Binding Sites Using Structural Knowledge
Abstract. Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structu...
Tommy Kaplan, Nir Friedman, Hanah Margalit
BIBM
2008
IEEE
137views Bioinformatics» more  BIBM 2008»
15 years 6 months ago
Exploring Alternative Splicing Features Using Support Vector Machines
Alternative splicing is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Finding alternative splicing events experimentally ...
Jing Xia, Doina Caragea, Susan Brown
GCB
2000
Springer
137views Biometrics» more  GCB 2000»
15 years 3 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
ATAL
2008
Springer
15 years 1 months ago
Cooperative search for optimizing pipeline operations
We present an application of a multi-agent cooperative search approach to the problem of optimizing gas pipeline operations, i.e. finding control parameters for a gas transmission...
T. Mora, Abu B. Sesay, Jörg Denzinger, Hossei...