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BMCBI
2004
200views more  BMCBI 2004»
14 years 11 months ago
ABC: software for interactive browsing of genomic multiple sequence alignment data
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
Gregory M. Cooper, Senthil A. G. Singaravelu, Aren...
WABI
2005
Springer
117views Bioinformatics» more  WABI 2005»
15 years 5 months ago
Faster Algorithms for Optimal Multiple Sequence Alignment Based on Pairwise Comparisons
Multiple Sequence Alignment (MSA) is one of the most fundamental problems in computational molecular biology. The running time of the best known scheme for finding an optimal ali...
Pankaj K. Agarwal, Yonatan Bilu, Rachel Kolodny
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BMCBI
2005
102views more  BMCBI 2005»
14 years 11 months ago
Genomic multiple sequence alignments: refinement using a genetic algorithm
Background: Genomic sequence data cannot be fully appreciated in isolation. Comparative genomics
Chunlin Wang, Elliot J. Lefkowitz
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
15 years 6 months ago
ChemAlign: Biologically Relevant Multiple Sequence Alignment Using Physicochemical Properties
—We present a new algorithm, ChemAlign, that uses physicochemical properties and secondary structure elements to create biologically relevant multiple sequence alignments (MSAs)....
Hyrum Carroll, Mark J. Clement, Quinn Snell, David...
WABI
2004
Springer
106views Bioinformatics» more  WABI 2004»
15 years 5 months ago
Suboptimal Local Alignments Across Multiple Scoring Schemes
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Morris Michael, Christoph Dieterich, Jens Stoye