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BMCBI
2005
130views more  BMCBI 2005»
14 years 11 months ago
Squid - a simple bioinformatics grid
Background: BLAST is a widely used genetic research tool for analysis of similarity between nucleotide and protein sequences. This paper presents a software application entitled &...
Paulo C. Carvalho, Rafael V. Glória, Antoni...
BMCBI
2005
103views more  BMCBI 2005»
14 years 11 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe
BMCBI
2005
104views more  BMCBI 2005»
14 years 11 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
BMCBI
2005
190views more  BMCBI 2005»
14 years 11 months ago
Species-specific analysis of protein sequence motifs using mutual information
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
Jan Hummel, Nima Keshvari, Wolfram Weckwerth, Joac...
BMCBI
2005
100views more  BMCBI 2005»
14 years 11 months ago
Evolutionary models for insertions and deletions in a probabilistic modeling framework
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
Elena Rivas