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RECOMB
2006
Springer
16 years 22 days ago
Alignment Statistics for Long-Range Correlated Genomic Sequences
It is well known that the base composition along eukaryotic genomes is long-range correlated. Here, we investigate the effect of such long-range correlations on alignment score sta...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
90
Voted
JCB
2007
107views more  JCB 2007»
15 years 9 days ago
Effects of Long-Range Correlations in DNA on Sequence Alignment Score Statistics
Long-range correlations in genomic base composition are a ubiquitous statistical feature among many eukaryotic genomes. In this article, these correlations are shown to substantia...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
NAR
2006
107views more  NAR 2006»
15 years 11 days ago
CorGen - measuring and generating long-range correlations for DNA sequence analysis
CorGen is a web server that measures long-range correlations in the base composition of DNA and generates random sequences with the same correlation parameters. Long-range correla...
Philipp W. Messer, Peter F. Arndt
BMCBI
2004
102views more  BMCBI 2004»
15 years 8 days ago
No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions
Background: Alternative splicing is an efficient mechanism for increasing the variety of functions fulfilled by proteins in a living cell. It has been previously demonstrated that...
Marc N. Offman, Ramil N. Nurtdinov, Mikhail S. Gel...
95
Voted
JCB
2000
91views more  JCB 2000»
15 years 6 days ago
Scaling Laws and Similarity Detection in Sequence Alignment with Gaps
We study the problem of similarity detection by sequence alignment with gaps, using a recently established theoretical framework based on the morphology of alignment paths. Alignm...
Dirk Drasdo, Terence Hwa, Michael Lässig