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» Alignment of Non-Overlapping Sequences
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153
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BMCBI
2004
105views more  BMCBI 2004»
15 years 3 months ago
eL-DASionator: an LDAS upload file generator
Background: The Distributed Annotation System (DAS) allows merging of DNA sequence annotations from multiple sources and provides a single annotation view. A straightforward way t...
Vincent Nègre, Christoph Grunau
137
Voted
RECOMB
2004
Springer
16 years 3 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
100
Voted
BIOINFORMATICS
2010
127views more  BIOINFORMATICS 2010»
15 years 3 months ago
Analyzing taxonomic classification using extensible Markov models
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming cl...
Rao M. Kotamarti, Michael Hahsler, Douglas Raiford...
125
Voted
BMCBI
2008
145views more  BMCBI 2008»
15 years 3 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
148
Voted
NAR
2008
125views more  NAR 2008»
15 years 3 months ago
Phylogeny.fr: robust phylogenetic analysis for the non-specialist
Phylogenetic analyses are central to many research areas in biology and typically involve the identification of homologous sequences, their multiple alignment, the phylogenetic re...
Alexis Dereeper, V. Guignon, G. Blanc, Stép...