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» Alignment of Non-Overlapping Sequences
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GECCO
2006
Springer
171views Optimization» more  GECCO 2006»
15 years 7 months ago
A hybrid genetic search for multiple sequence alignment
This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
Seung-Hyun Moon, Sung-Soon Choi, Byung Ro Moon
136
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BMCBI
2006
92views more  BMCBI 2006»
15 years 3 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
125
Voted
ARC
2007
Springer
123views Hardware» more  ARC 2007»
15 years 7 months ago
Multiple Sequence Alignment Using Reconfigurable Computing
The alignment of multiple protein (or DNA) sequences is a current problem in Bioinformatics. ClustalW is the most popular heuristic algorithm for multiple sequence alignment. Pairw...
Carlos R. Erig Lima, Heitor S. Lopes, Maiko R. Mor...
ISCAPDCS
2007
15 years 4 months ago
PARALLEL-TCOFFEE: A parallel multiple sequence aligner
In this paper we present a parallel implementation of T–Coffee — a widely used multiple sequence alignment package. Our software supports a majority of options provided by the...
Jaroslaw Zola, Xiao Yang, Adrian Rospondek, Sriniv...
CSB
2005
IEEE
110views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Maximum Sequence Alignment Fails to Predict Off-targeted Gene Regulation by RNAi
We have employed various sequence alignment algorithms and scoring techniques to determine whether current computational tools accurately predict genes that will be off-targeted b...
Amanda Birmingham, Emily M. Anderson, William S. M...