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» Alternating Refinement Relations
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104
Voted
BMCBI
2007
146views more  BMCBI 2007»
15 years 17 days ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
96
Voted
BMCBI
2008
111views more  BMCBI 2008»
15 years 17 days ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
107
Voted
BMCBI
2007
123views more  BMCBI 2007»
15 years 17 days ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
87
Voted
BMCBI
2008
244views more  BMCBI 2008»
15 years 17 days ago
RNAalifold: improved consensus structure prediction for RNA alignments
Background: The prediction of a consensus structure for a set of related RNAs is an important first step for subsequent analyses. RNAalifold, which computes the minimum energy str...
Stephan H. F. Bernhart, Ivo L. Hofacker, Sebastian...
159
Voted
BMCBI
2007
265views more  BMCBI 2007»
15 years 17 days ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...