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BMCBI
2006
117views more  BMCBI 2006»
15 years 5 months ago
The Cluster Variation Method for Efficient Linkage Analysis on Extended Pedigrees
Background: Computing exact multipoint LOD scores for extended pedigrees rapidly becomes infeasible as the number of markers and untyped individuals increase. When markers are exc...
Cornelis A. Albers, Martijn A. R. Leisink, Hilbert...
BMCBI
2006
114views more  BMCBI 2006»
15 years 5 months ago
A methodology for global validation of microarray experiments
Background: DNA microarrays are popular tools for measuring gene expression of biological samples. This ever increasing popularity is ensuring that a large number of microarray st...
Mathieu Miron, Owen Z. Woody, Alexandre Marcil, Ca...
BMCBI
2006
126views more  BMCBI 2006»
15 years 5 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
IANDC
2008
74views more  IANDC 2008»
15 years 5 months ago
Baire categories on small complexity classes and meager-comeager laws
We introduce two resource-bounded Baire category notions on small complexity classes such as P, QUASIPOLY, SUBEXP and PSPACE and on probabilistic classes such as BPP, which differ...
Philippe Moser
BMCBI
2006
125views more  BMCBI 2006»
15 years 5 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
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