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104
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BMCBI
2005
2005
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
14 years 9 months ago
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
BMCBI
2005
14 years 9 months ago
2005
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
100
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BMCBI
2005
14 years 9 months ago
2005
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
BMCBI
2005
14 years 9 months ago
2005
Background: Secondary structure is used in hierarchical classification of protein structures, identification of protein features, such as helix caps and loops, for fold recognitio...
BMCBI
2005
14 years 9 months ago
2005
Background: Clustering the ESTs from a large dataset representing a single species is a convenient starting point for a number of investigations into gene discovery, genome evolut...