Background: Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA ...
Christian Rohde, Yingying Zhang, Richard Reinhardt...
Background: Many high-throughput genomic experiments, such as Synthetic Genetic Array and yeast two-hybrid, use colony growth on solid media as a screen metric. These experiments ...
John C. Dittmar, Robert J. D. Reid, Rodney Rothste...
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Background: Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA microarrays. To this aim, existing cluster...
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...