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» Alternative implementations of the Griewangk function
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106
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BMCBI
2007
146views more  BMCBI 2007»
15 years 26 days ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
165
Voted
BMCBI
2007
265views more  BMCBI 2007»
15 years 26 days ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
100
Voted
BMCBI
2006
115views more  BMCBI 2006»
15 years 24 days ago
Multivariate curve resolution of time course microarray data
Background: Modeling of gene expression data from time course experiments often involves the use of linear models such as those obtained from principal component analysis (PCA), i...
Peter D. Wentzell, Tobias K. Karakach, Sushmita Ro...
JETAI
2008
114views more  JETAI 2008»
15 years 21 days ago
On the nature of minds, or: truth and consequences
Are minds really dynamical or are they really symbolic? Because minds are bundles of computations, and because computation is always a matter of interpretation of one system by an...
Shimon Edelman
117
Voted
BMCBI
2005
151views more  BMCBI 2005»
15 years 19 days ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang