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» Alternative splicing and protein function
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BMCBI
2008
135views more  BMCBI 2008»
14 years 11 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
CSB
2004
IEEE
125views Bioinformatics» more  CSB 2004»
15 years 3 months ago
Gene Length and Alternative Transcription in Fruit Fly
Alternative transcription, in which a single gene may give rise to multiple variant mRNA forms, is widely recognized as an important source of protein diversity in complex, eukary...
Boris Budagyan, Ann E. Loraine
BMCBI
2006
113views more  BMCBI 2006»
14 years 11 months ago
In silico discovery of human natural antisense transcripts
Background: Several high-throughput searches for ppotential natural antisense transcripts (NATs) have been performed recently, but most of the reports were focused on cis type. A ...
Yuan-Yuan Li, Lei Qin, Zong-Ming Guo, Lei Liu, Hao...
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BMCBI
2008
109views more  BMCBI 2008»
14 years 11 months ago
The meaning of alignment: lessons from structural diversity
Background: Protein structural alignment provides a fundamental basis for deriving principles of functional and evolutionary relationships. It is routinely used for structural cla...
Walter Pirovano, K. Anton Feenstra, Jaap Heringa
BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
14 years 11 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright