110 search results - page 13 / 22 » Alternative splicing and protein function |
BMCBI
2007
14 years 11 months ago
2007
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
BMCBI
2007
14 years 11 months ago
2007
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
BMCBI
2010
14 years 11 months ago
2010
Background: Scoring functions, such as molecular mechanic forcefields and statistical potentials are fundamentally important tools in protein structure modeling and quality assess...
BMCBI
2007
14 years 11 months ago
2007
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
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BMCBI
2010
14 years 6 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...