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» Alternative splicing and protein function
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BMCBI
2007
134views more  BMCBI 2007»
14 years 11 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
84
Voted
CANDC
2005
ACM
14 years 11 months ago
Overlapping genes in vertebrate genomes
Overlapping genes in mammalian genomes are unexpected phenomena even though hundreds of pairs of protein coding overlapping genes have been reported so far. Overlapping genes can ...
Izabela Makalowska, Chiao-Feng Lin, Wojciech Makal...
RECOMB
2002
Springer
15 years 12 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
104
Voted
RECOMB
2005
Springer
15 years 12 months ago
Learning Interpretable SVMs for Biological Sequence Classification
Background: Support Vector Machines (SVMs) ? using a variety of string kernels ? have been successfully applied to biological sequence classification problems. While SVMs achieve ...
Christin Schäfer, Gunnar Rätsch, Sö...
BMCBI
2007
90views more  BMCBI 2007»
14 years 11 months ago
Gene network interconnectedness and the generalized topological overlap measure
Background: Network methods are increasingly used to represent the interactions of genes and/ or proteins. Genes or proteins that are directly linked may have a similar biological...
Andy M. Yip, Steve Horvath