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» Alternative splicing and protein function
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BMCBI
2008
101views more  BMCBI 2008»
14 years 11 months ago
Reranking candidate gene models with cross-species comparison for improved gene prediction
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
Qian Liu, Koby Crammer, Fernando C. N. Pereira, Da...
BIOCOMP
2006
15 years 1 months ago
Identification of Intrinsically Unstructured Regions in Proteins Using Primary Structure
Most proteins function only when folded into a particular 3D configuration. Recently, a class of proteins has been discovered that do not fold into any particular configuration; t...
Mary Qu Yang, Jack Y. Yang
BMCBI
2006
165views more  BMCBI 2006»
14 years 11 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...
BMCBI
2004
122views more  BMCBI 2004»
14 years 11 months ago
A comprehensive comparison of comparative RNA structure prediction approaches
Background: An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, indep...
Paul P. Gardner, Robert Giegerich
LION
2009
Springer
112views Optimization» more  LION 2009»
15 years 6 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi