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BMCBI
2010
130views more  BMCBI 2010»
14 years 12 months ago
The behaviour of random forest permutation-based variable importance measures under predictor correlation
Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observ...
Kristin K. Nicodemus, James D. Malley, Carolin Str...
BMCBI
2010
117views more  BMCBI 2010»
14 years 12 months ago
Using jackknife to assess the quality of gene order phylogenies
Background: In recent years, gene order data has attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. If ge...
Jian Shi, Yiwei Zhang, Haiwei Luo, Jijun Tang
BMCBI
2010
156views more  BMCBI 2010»
14 years 12 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
BMCBI
2010
137views more  BMCBI 2010»
14 years 12 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
BMCBI
2010
89views more  BMCBI 2010»
14 years 12 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...