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» An Analysis of Inference with the Universum
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BMCBI
2005
131views more  BMCBI 2005»
14 years 9 months ago
Functional annotation by identification of local surface similarities: a novel tool for structural genomics
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
Fabrizio Ferrè, Gabriele Ausiello, Andreas ...
BMCBI
2005
116views more  BMCBI 2005»
14 years 9 months ago
A computational approach for identifying pathogenicity islands in prokaryotic genomes
Background: Pathogenicity islands (PAIs), distinct genomic segments of pathogens encoding virulence factors, represent a subgroup of genomic islands (GIs) that have been acquired ...
Sung Ho Yoon, Cheol-Goo Hur, Ho-Young Kang, Yeoun ...
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JCB
2007
198views more  JCB 2007»
14 years 9 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
TVCG
2008
122views more  TVCG 2008»
14 years 9 months ago
Interactive Entity Resolution in Relational Data: A Visual Analytic Tool and Its Evaluation
Databases often contain uncertain and imprecise references to real-world entities. Entity resolution, which is the process of reconciling multiple references to underlying real-wor...
Hyunmo Kang, Lise Getoor, Ben Shneiderman, Mustafa...
BMCBI
2004
162views more  BMCBI 2004»
14 years 9 months ago
Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant m
Background: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. Investigators manually inspect hundreds or thousands of expression p...
Rajalakshmi Gurunathan, Bernard Van Emden, Sethura...