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ALMOB
2008
85views more  ALMOB 2008»
14 years 9 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
BMCBI
2010
113views more  BMCBI 2010»
14 years 9 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
BMCBI
2006
133views more  BMCBI 2006»
14 years 9 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
BMCBI
2007
148views more  BMCBI 2007»
14 years 9 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
COLING
2002
14 years 9 months ago
The LinGO Redwoods Treebank: Motivation and Preliminary Applications
The LinGO Redwoods initiative is a seed activity in the design and development of a new type of treebank. While several medium- to large-scale treebanks exist for English (and for...
Stephan Oepen, Kristina Toutanova, Stuart M. Shieb...