21319 search results - page 3956 / 4264 » An Approach for Method Reengineering |
183
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BMCBI
2006
15 years 6 months ago
2006
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
141
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BMCBI
2006
15 years 6 months ago
2006
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
199
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BMCBI
2006
15 years 6 months ago
2006
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
169
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BMCBI
2006
15 years 6 months ago
2006
Background: Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining s...
165
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BMCBI
2006
15 years 6 months ago
2006
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...