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POPL
2005
ACM
16 years 4 months ago
Context logic and tree update
Spatial logics have been used to describe properties of treelike structures (Ambient Logic) and in a Hoare style to reason about dynamic updates of heap-like structures (Separatio...
Cristiano Calcagno, Philippa Gardner, Uri Zarfaty
RECOMB
2008
Springer
16 years 4 months ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
RECOMB
2008
Springer
16 years 4 months ago
Algorithms for Joint Optimization of Stability and Diversity in Planning Combinatorial Libraries of Chimeric Proteins
Abstract. In engineering protein variants by constructing and screening combinatorial libraries of chimeric proteins, two complementary and competing goals are desired: the new pro...
Wei Zheng, Alan M. Friedman, Chris Bailey-Kellogg
RECOMB
2004
Springer
16 years 4 months ago
The evolutionary capacity of protein structures
In nature, one finds large collections of different protein sequences exhibiting roughly the same three-dimensional structure, and this observation underpins the study of structur...
Leonid Meyerguz, David Kempe, Jon M. Kleinberg, Ro...
STOC
2004
ACM
145views Algorithms» more  STOC 2004»
16 years 4 months ago
Using mixture models for collaborative filtering
A collaborative filtering system at an e-commerce site or similar service uses data about aggregate user behavior to make recommendations tailored to specific user interests. We d...
Jon M. Kleinberg, Mark Sandler
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