Abstract--The now commonplace multi-core chips have introduced, by design, a deep hierarchy of memory and cache banks within parallel computers as a tradeoff between the user frien...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
William S. Sanders, Susan M. Bridges, Fiona M. McC...
A high-level understanding of how an application executes and which performance characteristics it exhibits is essential in many areas of high performance computing, such as applic...
Left unchecked, the fundamental drive to increase peak performance using tens of thousands of power hungry components will lead to intolerable operating costs and failure rates. H...