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PLDI
2010
ACM
15 years 3 months ago
Evaluating Iterative Optimization across 1000 Data Sets
While iterative optimization has become a popular compiler optimization approach, it is based on a premise which has never been truly evaluated: that it is possible to learn the b...
Yang Chen, Yuanjie Huang, Lieven Eeckhout, Grigori...
BMCBI
2008
114views more  BMCBI 2008»
14 years 12 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl
COMPUTER
1999
69views more  COMPUTER 1999»
14 years 11 months ago
Scientific Components Are Coming
abstract mathematical or physical statement, not something specific. The way scientific programmers most frequently verify that their programs are correct is to examine their resul...
Paul F. Dubois
BMCBI
2006
115views more  BMCBI 2006»
14 years 12 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan
JCB
2007
146views more  JCB 2007»
14 years 11 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...