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BMCBI
2010
156views more  BMCBI 2010»
14 years 10 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...
CPHYSICS
2006
182views more  CPHYSICS 2006»
14 years 10 months ago
MinFinder: Locating all the local minima of a function
A new stochastic clustering algorithm is introduced that aims to locate all the local minima of a multidimensional continuous and differentiable function inside a bounded domain. ...
Ioannis G. Tsoulos, Isaac E. Lagaris
WWW
2005
ACM
15 years 10 months ago
Topic segmentation of message hierarchies for indexing and navigation support
Message hierarchies in web discussion boards grow with new postings. Threads of messages evolve as new postings focus within or diverge from the original themes of the threads. Th...
Jong Wook Kim, K. Selçuk Candan, Mehmet Emi...
VLDB
1998
ACM
101views Database» more  VLDB 1998»
15 years 2 months ago
On Optimal Node Splitting for R-trees
The problem of finding an optimal bipartition of a rectangle set has a direct impact on query performance of dynamic R-trees. During update operations, overflowed nodes need to be...
Yván J. García, Mario A. Lopez, Scot...
SCAI
1993
14 years 11 months ago
A Case-Based Answer to Some Problems of Knowledge-Based Systems
Among the most important challenges for contemporary AI research are the development of methods for improved robustness, adaptability, and overall interactiveness of systems. Inter...
Agnar Aamodt