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» An Evolutionary Approach for Molecular Docking
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BMCBI
2006
115views more  BMCBI 2006»
13 years 6 months ago
The accuracy of several multiple sequence alignment programs for proteins
Background: There have been many algorithms and software programs implemented for the inference of multiple sequence alignments of protein and DNA sequences. The "true" ...
Paulo A. S. Nuin, Zhouzhi Wang, Elisabeth R. M. Ti...
BMCBI
2010
83views more  BMCBI 2010»
13 years 6 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf
BMCBI
2007
113views more  BMCBI 2007»
13 years 6 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
CMSB
2009
Springer
13 years 9 months ago
Control Strategies for the Regulation of the Eukaryotic Heat Shock Response
Abstract. Elevated temperatures cause proteins in living cells to misfold. They start forming larger and larger aggregates that can eventually lead to the cell's death. The he...
Elena Czeizler, Eugen Czeizler, Ralph-Johan Back, ...
TCS
2008
13 years 6 months ago
A small trip in the untranquil world of genomes: A survey on the detection and analysis of genome rearrangement breakpoints
Genomes are dynamic molecules that are constantly undergoing mutations and rearrangements. The latter are large scale changes in a genome organisation that participate in the evol...
Claire Lemaitre, Marie-France Sagot