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107
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BMCBI
2010
14 years 12 months ago
2010
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
BMCBI
2010
14 years 12 months ago
2010
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
111
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BMCBI
2010
2010
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
14 years 12 months ago
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
BMCBI
2010
14 years 12 months ago
2010
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
BMCBI
2010
14 years 12 months ago
2010
Background: Phylogenetic relationships between genes are not only of theoretical interest: they enable us to learn about human genes through the experimental work on their relativ...