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» An Improved Construction of Progression-Free Sets
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94
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BMCBI
2010
121views more  BMCBI 2010»
14 years 10 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
88
Voted
BMCBI
2008
142views more  BMCBI 2008»
14 years 10 months ago
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
Irene Kouskoumvekaki, Zhiyong Yang, Svava Ó...
BMCBI
2008
132views more  BMCBI 2008»
14 years 10 months ago
Mixture models for analysis of melting temperature data
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Christoffer Nellåker, Fredrik Uhrzander, Joa...
89
Voted
CN
2006
113views more  CN 2006»
14 years 10 months ago
Failure recovery for structured p2p networks: Protocol design and performance under churn
Measurement studies indicate a high rate of node dynamics in p2p systems. In this paper, we address the question of how high a rate of node dynamics can be supported by structured...
Simon S. Lam, Huaiyu Liu
89
Voted
BMCBI
2007
217views more  BMCBI 2007»
14 years 10 months ago
On consensus biomarker selection
Background: Recent development of mass spectrometry technology enabled the analysis of complex peptide mixtures. A lot of effort is currently devoted to the identification of biom...
Janusz Dutkowski, Anna Gambin