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BMCBI
2008
103views more  BMCBI 2008»
14 years 12 months ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe
BMCBI
2008
120views more  BMCBI 2008»
14 years 12 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
BMCBI
2008
101views more  BMCBI 2008»
14 years 12 months ago
Term-tissue specific models for prediction of gene ontology biological processes using transcriptional profiles of aging in dros
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...
Wensheng Zhang, Sige Zou, Jiuzhou Song
BMCBI
2008
129views more  BMCBI 2008»
14 years 12 months ago
Gene set enrichment analysis for non-monotone association and multiple experimental categories
Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
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CORR
2008
Springer
139views Education» more  CORR 2008»
14 years 11 months ago
Exact two-terminal reliability of some directed networks
Abstract-- The calculation of network reliability in a probabilistic context has long been an issue of practical and academic importance. Conventional approaches (determination of ...
Christian Tanguy