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» An Information Criterion for Informative Gene Selection
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BMCBI
2008
84views more  BMCBI 2008»
15 years 1 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
BMCBI
2010
185views more  BMCBI 2010»
14 years 8 months ago
MetaPIGA v2.0: maximum likelihood large phylogeny estimation using the metapopulation genetic algorithm and other stochastic heu
Background: The development, in the last decade, of stochastic heuristics implemented in robust application softwares has made large phylogeny inference a key step in most compara...
Raphaël Helaers, Michel C. Milinkovitch
KDD
2004
ACM
198views Data Mining» more  KDD 2004»
15 years 7 months ago
Mining traffic data from probe-car system for travel time prediction
We are developing a technique to predict travel time of a vehicle for an objective road section, based on real time traffic data collected through a probe-car system. In the area ...
Takayuki Nakata, Jun-ichi Takeuchi
GECCO
2010
Springer
211views Optimization» more  GECCO 2010»
15 years 2 months ago
Investigating EA solutions for approximate KKT conditions in smooth problems
Evolutionary algorithms (EAs) are increasingly being applied to solve real-parameter optimization problems due to their flexibility in handling complexities such as non-convexity,...
Rupesh Tulshyan, Ramnik Arora, Kalyanmoy Deb, Joyd...
IJON
1998
158views more  IJON 1998»
15 years 1 months ago
Bayesian Kullback Ying-Yang dependence reduction theory
Bayesian Kullback Ying—Yang dependence reduction system and theory is presented. Via stochastic approximation, implementable algorithms and criteria are given for parameter lear...
Lei Xu