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BMCBI
2006
148views more  BMCBI 2006»
15 years 1 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
BMCBI
2006
129views more  BMCBI 2006»
15 years 1 months ago
Functional clustering of yeast proteins from the protein-protein interaction network
Background: The abundant data available for protein interaction networks have not yet been fully understood. New types of analyses are needed to reveal organizational principles o...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BMCBI
2006
155views more  BMCBI 2006»
15 years 1 months ago
A powerful method for detecting differentially expressed genes from GeneChip arrays that does not require replicates
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Anne-Mette K. Hein, Sylvia Richardson
BMCBI
2006
141views more  BMCBI 2006»
15 years 1 months ago
The use of concept maps during knowledge elicitation in ontology development processes - the nutrigenomics use case
Background: Incorporation of ontologies into annotations has enabled 'semantic integration' of complex data, making explicit the knowledge within a certain field. One of...
Alexander García Castro, Philippe Rocca-Ser...
BMCBI
2006
96views more  BMCBI 2006»
15 years 1 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
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