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ICCS
2007
Springer
15 years 3 months ago
Using Computer Simulation to Understand Mutation Accumulation Dynamics and Genetic Load
Long-standing theoretical concerns about mutation accumulation within the human population can now be addressed with numerical simulation. We apply a biologically realistic forward...
John Sanford, John Baumgardner, Wes Brewer, Paul G...
HICSS
1997
IEEE
109views Biometrics» more  HICSS 1997»
15 years 2 months ago
Model-Integrated Programming
Model-integrated computing offers unique benefits for building computer-based systems. The tight integration of physical and information processess typical in CBSs is naturally ad...
Hubertus Franke, Janos Sztipanovits, Gabor Karsai
BMCBI
2007
109views more  BMCBI 2007»
14 years 10 months ago
TABASCO: A single molecule, base-pair resolved gene expression simulator
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
Sriram Kosuri, Jason R. Kelly, Drew Endy
BMCBI
2006
179views more  BMCBI 2006»
14 years 9 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
ACMSE
2006
ACM
15 years 3 months ago
Performance evaluation of the reactor pattern using the OMNeT++ simulator
The design of large-scale, distributed, performance-sensitive systems presents numerous challenges due to their networkcentric nature and stringent quality of service (QoS) requir...
Arundhati Kogekar, Aniruddha S. Gokhale