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SIAMCOMP
2012
13 years 7 months ago
Randomized Competitive Algorithms for Generalized Caching
We consider online algorithms for the generalized caching problem. Here we are given a cache of size k and pages with arbitrary sizes and fetching costs. Given a request sequence ...
Nikhil Bansal, Niv Buchbinder, Joseph Naor
BMCBI
2010
125views more  BMCBI 2010»
15 years 5 months ago
In-silico prediction of blood-secretory human proteins using a ranking algorithm
Background: Computational identification of blood-secretory proteins, especially proteins with differentially expressed genes in diseased tissues, can provide highly useful inform...
Qi Liu, Juan Cui, Qiang Yang, Ying Xu
BMCBI
2010
116views more  BMCBI 2010»
15 years 5 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
ICML
2006
IEEE
16 years 6 months ago
Using inaccurate models in reinforcement learning
In the model-based policy search approach to reinforcement learning (RL), policies are found using a model (or "simulator") of the Markov decision process. However, for ...
Pieter Abbeel, Morgan Quigley, Andrew Y. Ng
JUCS
2010
162views more  JUCS 2010»
14 years 12 months ago
UML Behavior Models of Real-Time Embedded Software for Model-Driven Architecture
Abstract: Model-Driven Architecture (MDA) presents a set of layered models to separate design concerns from platform concerns. The model executability for each model element is sti...
Jin Hyun Kim, Jin-Young Choi, Inhye Kang, Insup Le...