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100
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: Integration of multiple results from Quantitative Trait Loci (QTL) studies is a key point to understand the genetic determinism of complex traits. Up to now many effor...
BMCBI
2008
14 years 10 months ago
2008
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
BMCBI
2007
14 years 10 months ago
2007
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
BMCBI
2008
14 years 10 months ago
2008
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
82
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...