Drawing on the correspondence between the graph Laplacian, the Laplace-Beltrami operator on a manifold, and the connections to the heat equation, we propose a geometrically motiva...
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
Background: Recent technological advances in high-throughput data collection allow for experimental study of increasingly complex systems on the scale of the whole cellular genome...
Bahrad A. Sokhansanj, J. Patrick Fitch, Judy N. Qu...
Cloud Computing has been envisioned as the next-generation architecture of IT Enterprise. It moves the application software and databases to the centralized large data centers, whe...
Qian Wang, Cong Wang, Jin Li, Kui Ren, Wenjing Lou
This article describes an application of the partially observable Markov (POM) model to the analysis of a large scale commercial web search log. Mathematically, POM is a variant o...