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» An analysis of diversity measures
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110
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BMCBI
2010
110views more  BMCBI 2010»
15 years 25 days ago
Missing value imputation for epistatic MAPs
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
Colm Ryan, Derek Greene, Gerard Cagney, Padraig Cu...
112
Voted
BMCBI
2010
109views more  BMCBI 2010»
15 years 24 days ago
ParallABEL: an R library for generalized parallelization of genome-wide association studies
Background: Genome-Wide Association (GWA) analysis is a powerful method for identifying loci associated with complex traits and drug response. Parts of GWA analyses, especially th...
Unitsa Sangket, Surakameth Mahasirimongkol, Wasun ...
95
Voted
BMCBI
2010
160views more  BMCBI 2010»
15 years 24 days ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
85
Voted
BMCBI
2007
147views more  BMCBI 2007»
15 years 24 days ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
122
Voted
BMCBI
2008
202views more  BMCBI 2008»
15 years 24 days ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
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