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BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
SDM
2004
SIAM
187views Data Mining» more  SDM 2004»
14 years 11 months ago
Minimum Sum-Squared Residue Co-Clustering of Gene Expression Data
Microarray experiments have been extensively used for simultaneously measuring DNA expression levels of thousands of genes in genome research. A key step in the analysis of gene e...
Hyuk Cho, Inderjit S. Dhillon, Yuqiang Guan, Suvri...
FSS
2002
99views more  FSS 2002»
14 years 9 months ago
Extreme physical information and objective function in fuzzy clustering
Fuzzy clustering algorithms have been widely studied and applied in a variety of areas. They become the major techniques7 in cluster analysis. In this paper, we focus on objective...
Michel Ménard, Michel Eboueya
BMCBI
2004
106views more  BMCBI 2004»
14 years 9 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
BMCBI
2011
14 years 1 months ago
Robust joint analysis allowing for model uncertainty in two-stage genetic association studies
Background: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex di...
Dongdong Pan, Qizhai Li, Ningning Jiang, Aiyi Liu,...