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BMCBI
2010
136views more  BMCBI 2010»
14 years 9 months ago
An integrated Bayesian analysis of LOH and copy number data
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
BIBE
2007
IEEE
148views Bioinformatics» more  BIBE 2007»
15 years 4 months ago
A New Smoothing Model for Analyzing Array CGH Data
—Array based Comparative Genomic Hybridization (CGH) is a molecular cytogenetic method for the detection of chromosomal imbalances and it has been extensively used for studying c...
Nha Nguyen, Heng Huang, Soontorn Oraintara, An P. ...
BMCBI
2010
139views more  BMCBI 2010»
14 years 9 months ago
TOPSAN: a collaborative annotation environment for structural genomics
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
Dana Weekes, S. Sri Krishna, Constantina Bakolitsa...
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BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch
BMCBI
2006
103views more  BMCBI 2006»
14 years 9 months ago
Statistical inference of chromosomal homology based on gene colinearity and applications to Arabidopsis and rice
Background: The identification of chromosomal homology will shed light on such mysteries of genome evolution as DNA duplication, rearrangement and loss. Several approaches have be...
Xiyin Wang, Xiaoli Shi, Zhe Li, Qihui Zhu, Lei Kon...