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BMCBI
2005
131views more  BMCBI 2005»
14 years 9 months ago
Functional annotation by identification of local surface similarities: a novel tool for structural genomics
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
Fabrizio Ferrè, Gabriele Ausiello, Andreas ...
BMCBI
2007
145views more  BMCBI 2007»
14 years 9 months ago
Colony size measurement of the yeast gene deletion strains for functional genomics
Background: Numerous functional genomics approaches have been developed to study the model organism yeast, Saccharomyces cerevisiae, with the aim of systematically understanding t...
Negar Memarian, Matthew Jessulat, Javad Alirezaie,...
JSW
2007
66views more  JSW 2007»
14 years 9 months ago
Implementing Model-Based Data Structures using Transient Model Extensions
— Software is often constructed using a layered approach to encapsulate various functionality in corresponding layers. Individual requirements of each layer demand layer specifi...
Michael Thonhauser, Gernot Schmoelzer, Christian K...
76
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BMCBI
2007
183views more  BMCBI 2007»
14 years 9 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
85
Voted
NIPS
2003
14 years 11 months ago
ICA-based Clustering of Genes from Microarray Expression Data
We propose an unsupervised methodology using independent component analysis (ICA) to cluster genes from DNA microarray data. Based on an ICA mixture model of genomic expression pa...
Su-In Lee, Serafim Batzoglou