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BMCBI
2007
145views more  BMCBI 2007»
14 years 9 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
CANDC
2004
ACM
14 years 9 months ago
The iProClass integrated database for protein functional analysis
Increasingly, scientists have begun to tackle gene functions and other complex regulatory processes by studying organisms at the global scales for various levels of biological org...
Cathy H. Wu, Hongzhan Huang, Anastasia N. Nikolska...
RECONFIG
2009
IEEE
182views VLSI» more  RECONFIG 2009»
15 years 4 months ago
Scalability Studies of the BLASTn Scan and Ungapped Extension Functions
BLASTn is a ubiquitous tool used for large scale DNA analysis. Detailed profiling tests reveal that the most computationally intensive sections of the BLASTn algorithm are the sc...
Siddhartha Datta, Ron Sass
80
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BMCBI
2002
188views more  BMCBI 2002»
14 years 9 months ago
The limit fold change model: A practical approach for selecting differentially expressed genes from microarray data
Background: The biomedical community is developing new methods of data analysis to more efficiently process the massive data sets produced by microarray experiments. Systematic an...
David M. Mutch, Alvin Berger, Robert Mansourian, A...
BMCBI
2004
146views more  BMCBI 2004»
14 years 9 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker