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BMCBI
2010
144views more  BMCBI 2010»
14 years 9 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
BMCBI
2007
146views more  BMCBI 2007»
14 years 9 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
CPM
2004
Springer
108views Combinatorics» more  CPM 2004»
15 years 3 months ago
Quadratic Time Algorithms for Finding Common Intervals in Two and More Sequences
A popular approach in comparative genomics is to locate groups or clusters of orthologous genes in multiple genomes and to postulate functional association between the genes contai...
Thomas Schmidt, Jens Stoye
BIOCOMP
2009
14 years 7 months ago
Gene Expression Analysis Using Communications, Coding and Information Theory Based Models
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...
Mohammad Al Bataineh, Lun Huang, Ismaeel Muhamed, ...
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BMCBI
2010
100views more  BMCBI 2010»
14 years 9 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...