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ISMB
2007
15 years 15 days ago
A Chado case study: an ontology-based modular schema for representing genome-associated biological information
Motivation: A few years ago, FlyBase undertook to design a new database schema to store Drosophila data. It would fully integrate genomic sequence and annotation data with bibliog...
Chris Mungall, David B. Emmert
76
Voted
BMCBI
2008
179views more  BMCBI 2008»
14 years 10 months ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
BMCBI
2008
87views more  BMCBI 2008»
14 years 10 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
87
Voted
MOBICOM
2004
ACM
15 years 3 months ago
Revisiting the TTL-based controlled flooding search: optimality and randomization
In this paper we consider the problem of searching for a node or an object (i.e., piece of data, file, etc.) in a large network. Applications of this problem include searching fo...
Nicholas B. Chang, Mingyan Liu
SIGSOFT
2006
ACM
15 years 11 months ago
Scenarios, goals, and state machines: a win-win partnership for model synthesis
Models are increasingly recognized as an effective means for elaborating requirements and exploring designs. For complex systems, model building is far from an easy task. Efforts ...
Christophe Damas, Bernard Lambeau, Axel van Lamswe...