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BMCBI
2010
105views more  BMCBI 2010»
14 years 9 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
178views more  BMCBI 2010»
14 years 9 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader
BMCBI
2010
96views more  BMCBI 2010»
14 years 9 months ago
OpenChrom: a cross-platform open source software for the mass spectrometric analysis of chromatographic data
Background: Today, data evaluation has become a bottleneck in chromatographic science. Analytical instruments equipped with automated samplers yield large amounts of measurement d...
Philip Wenig, Juergen Odermatt
CORR
2010
Springer
180views Education» more  CORR 2010»
14 years 9 months ago
Dependability in Aggregation by Averaging
Abstract. Aggregation is an important building block of modern distributed applications, allowing the determination of meaningful properties (e.g. network size, total storage capac...
Paulo Jesus, Carlos Baquero, Paulo Sérgio A...
CORR
2010
Springer
137views Education» more  CORR 2010»
14 years 9 months ago
Open Graphs and Monoidal Theories
String diagrams are a powerful tool for reasoning about physical processes, logic circuits, tensor networks, and many other compositional structures. The distinguishing feature of...
Lucas Dixon, Aleks Kissinger
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