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BMCBI
2008
102views more  BMCBI 2008»
14 years 11 months ago
Improving protein function prediction methods with integrated literature data
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
Aaron Gabow, Sonia M. Leach, William A. Baumgartne...
ICMLA
2004
15 years 1 months ago
PolyCluster: an interactive visualization approach to construct classification rules
This paper introduces a system, called PolyCluster, which adopts state-of-the-art algorithms for data visualization and integrates human domain knowledge into the construction pro...
Danyu Liu, Alan P. Sprague, Jeffrey G. Gray
BIBM
2007
IEEE
15 years 6 months ago
A Semi-supervised Learning Approach to Disease Gene Prediction
Discovering human disease-causing genes (disease genes in short) is one of the most challenging problems in bioinformatics and biomedicine, as most diseases are related in some wa...
Thanh Phuong Nguyen, Tu Bao Ho
BMCBI
2006
148views more  BMCBI 2006»
14 years 11 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
BMCBI
2006
184views more  BMCBI 2006»
14 years 11 months ago
PathSys: integrating molecular interaction graphs for systems biology
Background: The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low th...
Michael Baitaluk, Xufei Qian, Shubhada Godbole, Al...