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BMCBI
2008
155views more  BMCBI 2008»
14 years 11 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BMCBI
2010
127views more  BMCBI 2010»
14 years 11 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2011
14 years 3 months ago
Acorn: A grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks v
Background: Constraint-based approaches facilitate the prediction of cellular metabolic capabilities, based, in turn on predictions of the repertoire of enzymes encoded in the gen...
Jacek Sroka, Lukasz Bieniasz-Krzywiec, Szymon Gwoz...
ICCS
2007
Springer
15 years 5 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
CE
2007
176views more  CE 2007»
14 years 11 months ago
Pedagogical approaches for technology-integrated science teaching
The two separate projects described have examined how teachers exploit computer-based technologies in supporting learning of science at secondary level. This paper examines how pe...
Sara Hennessy, Jocelyn Wishart, Denise Whitelock, ...