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BMCBI
2007
169views more  BMCBI 2007»
14 years 12 months ago
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
CONCURRENCY
2010
130views more  CONCURRENCY 2010»
14 years 12 months ago
Enabling high-speed asynchronous data extraction and transfer using DART
As the complexity and scale of current scientific and engineering applications grow, managing and transporting the large amounts of data they generate is quickly becoming a signif...
Ciprian Docan, Manish Parashar, Scott Klasky
BMCBI
2006
129views more  BMCBI 2006»
14 years 12 months ago
A literature-based similarity metric for biological processes
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
BMCBI
2006
122views more  BMCBI 2006»
14 years 12 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2007
166views more  BMCBI 2007»
14 years 11 months ago
Data handling strategies for high throughput pyrosequencers
Background: New high throughput pyrosequencers such as the 454 Life Sciences GS 20 are capable of massively parallelizing DNA sequencing providing an unprecedented rate of output ...
Gabriele A. Trombetti, Raoul J. P. Bonnal, Ermanno...