We describe the informatics requirements of translational biomedical research projects and how e-Science tools can be used to address them. We use pattern templates to describe the...
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...