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BIBM
2009
IEEE
155views Bioinformatics» more  BIBM 2009»
15 years 4 months ago
Towards Reliable Isoform Quantification Using RNA-Seq Data
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
Brian E. Howard, Steffen Heber
IJCNN
2008
IEEE
15 years 4 months ago
Comparative study on normalization procedures for cluster analysis of gene expression datasets
—Normalization before clustering is often needed for proximity indices, such as Euclidian distance, which are sensitive to differences in the magnitude or scales of the attribute...
Marcílio Carlos Pereira de Souto, Daniel S....
CEC
2009
IEEE
15 years 2 months ago
A model for intrinsic artificial development featuring structural feedback and emergent growth
Abstract--A model for intrinsic artificial development is introduced in this paper. The proposed model features a novel mechanism where growth emerges, rather than being triggered ...
Martin Trefzer, Tüze Kuyucu, Julian Francis M...
BMCBI
2010
84views more  BMCBI 2010»
14 years 10 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
BMCBI
2010
97views more  BMCBI 2010»
14 years 5 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...